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However, because of the shortage of commercially available Retin-A Tretinoin Cream 0.1%, it is compounded by Compounding Pharmacy of Manitoba. For a compounded Tretinoin Cream formulation, the ‘Beyond Use Date (BUD) is not later than 30 days (See Table 4 below).
Non-sterile preparations are compounded for immediate use or for short-term storage; therefore, their BUDs are assigned on the basis of criteria different from those applied in assigning an expiry date to manufactured drug products.
In the absence of any stability data for a drug or a specific non-sterile compounded preparation, Table 4 presents maximum BUDs recommended for non-sterile compounded preparations that are packaged in air-tight, ligh-tresistant containers and stored at controlled room temperature.
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